Graphene-based mostly implantable engineering paves way for significant-precision therapeutic programs

Preparing of the porous lowered GO slim-movie EGNITE. This consists of filtering a GO solution via a porous membrane (1, 2), transferring the deposited film of stacked GO flakes onto a conductive substrate (3) and the hydrothermal reduction of the ensemble, which turns the movie really porous and conductive (4). Credit: Mother nature Nanotechnology (2024). DOI: 10.1038/s41565-023-01570-5

Yrs of investigate has led to the improvement of EGNITE (Engineered Graphene for Neural Interfaces), a novel class of flexible, higher-resolution, substantial-precision graphene-centered implantable neurotechnology.

The study printed nowadays (Jan. 11) in Mother nature Nanotechnology adds an innovative technological know-how to the blooming landscape of neuroelectronics and brain-laptop or computer interfaces.

EGNITE builds on the large working experience of its inventors in the fabrication and professional medical translation of carbon nanomaterials. This progressive engineering based mostly on nanoporous graphene integrates fabrication processes conventional in the semiconductor field to assemble graphene microelectrodes of a mere 25 µm in diameter. The graphene microelectrodes exhibit low impedance and higher charge injection, essential attributes for flexible and economical neural interfaces.

Preclinical reports by a variety of neuroscience and biomedical authorities that partnered with ICN2, using unique products for equally the central and peripheral nervous process, demonstrated the capacity of EGNITE in recording high-fidelity neural signals with excellent clarity and precision and, more importantly, pay for very focused nerve modulation. The distinctive blend of significant-fidelity sign recording and precise nerve stimulation made available by EGNITE engineering signifies a possibly critical advancement in neuroelectronic therapeutics.

This innovative approach addresses a crucial hole in neurotechnology, which has witnessed little improvement in products more than the very last two decades. The advancement of EGNITE electrodes has the capability to spot graphene at the forefront of neurotechnological materials.

More information:
Damià Viana et al, Nanoporous graphene-dependent slim-film microelectrodes for in vivo high-resolution neural recording and stimulation, Mother nature Nanotechnology (2024). DOI: 10.1038/s41565-023-01570-5

Presented by
Autonomous College of Barcelona


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Graphene-primarily based implantable technology paves way for substantial-precision therapeutic applications (2024, January 11)
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